Mohammed, M., AbddelMoneim, W., NM, G., Fawzy, M., Ramadan, A., Abellah, N. (2022). Toxicological Analysis of Synthetic Cannabinoids (Strox) Seized in Assiut Governorate Using Gas Chromatography/ Mass Spectrophotometry (GC/MS).. Zagazig Journal of Forensic Medicine and Toxicology, 20(2), 286-302. doi: 10.21608/zjfm.2022.114492.1101
Marwa Kh. Mohammed; Wafaa M. AbddelMoneim; Ghandour NM; Mohamed Fawzy; Abdelrahman Ramadan; Nora Z. Abellah. "Toxicological Analysis of Synthetic Cannabinoids (Strox) Seized in Assiut Governorate Using Gas Chromatography/ Mass Spectrophotometry (GC/MS).". Zagazig Journal of Forensic Medicine and Toxicology, 20, 2, 2022, 286-302. doi: 10.21608/zjfm.2022.114492.1101
Mohammed, M., AbddelMoneim, W., NM, G., Fawzy, M., Ramadan, A., Abellah, N. (2022). 'Toxicological Analysis of Synthetic Cannabinoids (Strox) Seized in Assiut Governorate Using Gas Chromatography/ Mass Spectrophotometry (GC/MS).', Zagazig Journal of Forensic Medicine and Toxicology, 20(2), pp. 286-302. doi: 10.21608/zjfm.2022.114492.1101
Mohammed, M., AbddelMoneim, W., NM, G., Fawzy, M., Ramadan, A., Abellah, N. Toxicological Analysis of Synthetic Cannabinoids (Strox) Seized in Assiut Governorate Using Gas Chromatography/ Mass Spectrophotometry (GC/MS).. Zagazig Journal of Forensic Medicine and Toxicology, 2022; 20(2): 286-302. doi: 10.21608/zjfm.2022.114492.1101
Toxicological Analysis of Synthetic Cannabinoids (Strox) Seized in Assiut Governorate Using Gas Chromatography/ Mass Spectrophotometry (GC/MS).
1Assistant lecturer of Forensic Medicine and Clinical Toxicology, Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut University, Egypt
2Department of Forensic Medicine and Clinical Toxicology, Faculty of Medicine, Assiut University
3Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut University, Egypt
4Neurology and Psychiatry Department - Faculty of Medicine – Assiut University.
5House Officer, Assiut University Hospital.
6Assistant Professor of Forensic Medicine and Clinical Toxicology, Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Assiut University, Egypt
Abstract
Background: In recent years many unknown synthetic cannabinoids (SCs) and other components have appeared on the market as constituents of herbal mixtures known as (Strox) which is posing a major public health and legal risk for society. Additionally, there is no adequate data on the ingredients of the illegally available ‘Strox’ and their pharmacological properties .Aim: this study was conducted to to detect active principles of some SCs products and to investigate the diversity of available synthetic cannabinoids (Strox) in Assiut governorate in 2020. Methodology: analysis of synthetic cannabinoid extract from 3 different seized samples (Strox) was conducted using Gas chromatography/ mass Spectrophotometry (GC/MS). Results: The Gas chromatography/ mass Spectrophotometry (GC/MS) analysis revealed that the different seized SCs samples were significantly different in terms of the active ingredients. Those ingredients included fatty acids, tobacco derivatives, cannabis sativa derivatives, benzodiazepines, quinazoline derivatives, piperine, indoles, analgesic agents, alkanes, melatonin derivatives, arsenic, solvents, and benzoic acid. Conclusion: The illegally available SCs samples have different ingredients which reflect the difference in the expected effects on users and making diagnosis of SCs use is challenging. Thus, leading to unpredictability of experienced symptoms and clinical presentation. Recommendations: Given the continuous emergence of variable mixtures containing new synthetic cannabinoids, a widespread cooperation system is necessary for sharing analytical information and improving drug market monitoring. This cooperation is mandatory to keep an up-to-date list of controlled substances. Key words Strox, New Psychoactive, Synthetic Cannabinoids, GC/MS, illegal herbal mixture.
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