Abdelkader, M., Elsayed, R., Shokry, M. (2023). Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment. Zagazig Journal of Forensic Medicine and Toxicology, 21(1), 133-156. doi: 10.21608/zjfm.2023.180421.1133
Mai Abdelkader; Reda Elsayed; Meray Medhat Shokry. "Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment". Zagazig Journal of Forensic Medicine and Toxicology, 21, 1, 2023, 133-156. doi: 10.21608/zjfm.2023.180421.1133
Abdelkader, M., Elsayed, R., Shokry, M. (2023). 'Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment', Zagazig Journal of Forensic Medicine and Toxicology, 21(1), pp. 133-156. doi: 10.21608/zjfm.2023.180421.1133
Abdelkader, M., Elsayed, R., Shokry, M. Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment. Zagazig Journal of Forensic Medicine and Toxicology, 2023; 21(1): 133-156. doi: 10.21608/zjfm.2023.180421.1133
Pattern and Outcome of Acute Aluminium Phosphide Intoxicated Cases at Sohag University Hospitals: Special Consideration to Paraffin Oil as a Supportive Treatment
1forensic medicine and clinical toxicology, faculty of medicine, sohage university, sohage
2department of forensic medicine and clinical toxicology, faculty of medicine, Sohag university
3Department of forensic medicine and clinical toxicology, faculty of medicine Sohag university
Abstract
Introduction: In the last years poisoning by aluminium phosphide (AlP) became a common method of suicide with high mortality rates. Aim of the work: The study aimed to evaluate the characters and outcome of acute aluminum phosphide intoxicated cases at Sohag university hospitals. Patients and methods: It is a cross sectional study conducted on acutely AlP intoxicated patients attended Sohag university hospitals including a retrospective part from January 2020 to December 2021(23 case) and a prospective part from January 2022 to June 2022 (41 case). Demographic data, mode of poisoning, route of administration, amount taken, delay time, vital signs, degree of coma, ejection fraction, troponin I and creatinine levels and first aid measures were recorded then related them to the patient outcome. Results: the incidence of ALP toxicity increased every year, in 2020 was 10.9%, in 2021 (25%), while, in the first half of 2022 it was 64.1%. The mean age was 21.7± 10.65 with male predominance by 53.1%. There was a significant increase in percentage of survived patients decontaminated by paraffin oil (84.6%) compared to other methods (15.4%). Receiver operating characteristic curve (ROC) was used to assess predictors of mortality in acute ALP-poisoned patients. The accuracy rate of ejection fraction, poisoning severity score (PSS), dose, serum troponin I, systolic blood pressure, delay time, and HCO3 were 100%, 97.7%, 94.4%, 93.7%, 89.5%, 81.9%, and 80.1% respectively with excellent discrimination. Diastolic blood pressure (77.9%) and PH (75.2%) with acceptable discrimination. While, creatinine and GCS gave non-acceptable discrimination. Conclusion: the frequency of suicidal ingestion of ALP is increasing every year. Decontamination by paraffin oil and early presentation had a better prognosis. At admission assessment of ejection fraction, PSS, serum troponin and creatinine, blood pressure, ABG have a beneficial role as predictors of mortality and emergency intervention to cases with probable bad prognosis.
View on SCiNiTO
Top